Proteomics profiling of a pre-metastatic colorectal cancer cohort identifies four proteomics-based subtypes and highlights ...

Alkanediols such as 1,6-hexanediol disrupt many phase-separated condensates in cellula and in vitro, but how molecular interactions are perturbed by these compounds remains unclear. This study uses ...

I was at a cancer meeting in Brisbane when the question about the culture of a community occurred to me. The meeting was well ...

Top-down proteomics: Intact proteins are ionized and analyzed directly, allowing for the study of proteoforms and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein Kinase A (PKA) is regulated spatially ...

This month's cover highlights the article AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo by Marina Pavlou, Thomas A. Reh and colleagues. Injuring ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Type 2 diabetes (T2D) presents a global health ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Primary cilia are solitary organelles formed ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The necrosome is the key macromolecular ...