Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

1Combination Strategies for Translational Immunotherapy, Immunology and Immunotherapy Program, Centro de Investigación Médica Aplicada (CIMA) Universidad de Navarra, Pamplona, Spain. 2Department of ...

Salk Institute for Biological Studies, la jolla, CA, United States ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

3Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. *Corresponding Author: David A. Reardon, Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.

1Northwestern University, Chicago, Illinois.

Major Finding: Elevated bile acids (BA) in liver cancer contribute to T-cell dysfunction. Concept: BA accumulation in T cells promotes ER stress, reducing effector function and viability. Impact: ...

1Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee. *Corresponding Author: Brent A. Orr, Department of Pathology, St. Jude Children ...

1Department of Biology, University of Rochester, Rochester, New York. Search for other works by this author on: 2Westlake Disease Modeling Lab, Westlake Laboratory of Life Sciences and Biomedicine, ...

Although it has risen from 7% over the past decade, the relative 5-year survival rate for pancreatic cancer is 13%, the same rate as reported last year, according to the just released American Cancer ...

1Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas. 2Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, ...